RecruitingCOPD (Chronic Obstructive Pulmonary Disease)Chronic Obstructive Pulmonary Disease (COPD)
Nebulizer Versus Handheld Maintenance Therapy for Patients With COPD
Eligible age
60+ yrs
Accepts
All genders
Locations
2 states
Healthy volunteers
No
See if you qualify for this study
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About this study
Multi-site, randomized controlled trial to determine whether patients who report NO symptomatic benefit with their maintenance hand-held inhaler(s), benefit upon switching to nebulized therapy using comparable classes of medications.
Sponsor: COPD Foundation
You may qualify if…
- ✓ \> 10 pack-years smoking cigarettes
- ✓ Diagnosis of COPD based on GOLD Criteria
- ✓ Patients are clinically stable for the past 4 weeks
- ✓ Prior Pulmonary function tests showing FEV1 \< 50% predicted (either 30 minutes post albuterol or within 2-4 hours after using their maintenance long-acting inhaler) within the past 12 months.
- ✓ Currently using a single pMDI or a single DPI with either LABA/LAMA or LABA/LAMA/ICS therapy for at least one month.
You may not qualify if…
- ✕ Current diagnosis of dementia or known cognitive impairment.
- ✕ Current impairment in manual dexterity (i.e., severe rheumatoid arthritis, severe tremor, etc)
- ✕ Exacerbation of COPD within the last 2 months
- ✕ Current diagnosis of other respiratory disease including asthma, treatment with a LABA/LAMA slow mist inhaler or treatment with SABA/SAMA nebulizer medications 3-4 times per day as maintenance therapy
- ✕ Current use of daily Prednisone as treatment for COPD
Where it's recruiting
Missouri
Saint Charles
North Carolina
Winston-Salem
Source: ClinicalTrials.gov · NCT07816835 · last updated 2026-09-14