RecruitingOverweightObesity
A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity
Eligible age
18–55 yrs
Accepts
All genders
Locations
2 states
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The purpose of the study is to find out if NNC0721-8060 is safe and how it works in people living with overweight or obesity.
Sponsor: Novo Nordisk A/S
You may qualify if…
- ✓ Male or female (sex at birth).
- ✓ Age 18-55 years (both inclusive) at the time of signing informed consent.
- ✓ Body Mass Index (BMI) 27.0-34.9 kilograms per square metre (kg/m\^2) (both inclusive) at screening, with overweight due to excess adipose tissue as judged by the investigator.
- ✓ Considered eligible based on medical history, physical examination, vital signs, electrocardiogram and clinical laboratory tests at screening, as judged by the investigator.
You may not qualify if…
- ✕ Known or suspected hypersensitivity to study intervention(s) or related products.
- ✕ Previous randomisation in this study.
- ✕ History of allergies (with the exception of seasonal allergies) or history of anaphylactic reactions.
- ✕ Female who is pregnant, breastfeeding, intends to become pregnant, or is of childbearing potential and not using adequate contraception.
- ✕ Current participation (signed informed consent) in any other interventional clinical study.
- ✕ Exposure to an investigational medicinal product within 30 days or five half-lives of that product (whichever is longer) before screening.
- ✕ Any disorder, unwillingness or inability which, in the investigator's opinion, might jeopardise participant safety or compliance with the protocol.
- ✕ Glycated haemoglobin (HbA1c) greater than or equal to (≥) 6.5 percentage (%) (48 millimoles per mole \[mmol/mol\]) at screening.
Where it's recruiting
Source: ClinicalTrials.gov · NCT07767175 · last updated 2026-09-04