RecruitingSpinal Cord InjuryStroke (CVA) or Transient Ischemic AttackMultiple Sclerosis
Understanding and Enhancing Human Health and Movement
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
By doing this study, investigators hope to learn how electrical stimulation can improve human movement, biomechanics, and function and to gather information on the safety and effectiveness of an implanted electrical stimulation system after paralysis from spinal cord injury, stroke, multiple sclerosis, and traumatic brain injury.
Sponsor: Louis Stokes VA Medical Center
You may qualify if…
- ✓ Skeletal maturity and ability to sign informed consent (\>18 years)
- ✓ Non-ventilator dependent paralysis resulting from injuries such as: mid cervical/thoracic (C4 or below) spinal cord injuries, poststroke hemiparesis, TBI, or MS, affecting the trunk and/or lower limbs
- ✓ Innervated and excitable lower extremity and trunk musculature
- ✓ Adequate social support and stability
- ✓ Willingness to comply with follow-up procedures
- ✓ Time post injury greater than six months
- ✓ Appropriate body habitus (height and weight within acceptable limits as determined by study physician)
- ✓ Neurologically stable as determined by a physician
You may not qualify if…
- ✕ Non-English speaking
- ✕ Females who are pregnant
- ✕ Current pressure injuries that would be exacerbated by study activities
- ✕ Severe contractures or uncontrolled spasticity of any major joint of the upper or lower extremities that results in a fixed deformity that would interfere with study activities
- ✕ History of spontaneous fractures or other evidence of excessively low bone density
- ✕ History of vestibular dysfunction, balance problems, or spontaneous falls
- ✕ Acute and or/untreated orthopedic problems that would prevent a participant from weight bearing or exercising such as a dislocation or fracture.
- ✕ Acute and/or chronic problems left untreated or not controlled that would put a participant at risk by using stimulation such as cardiac abnormalities, immunological/pulmonary/renal/circulatory compromise, diabetes or hypertension
Where it's recruiting
Ohio
Cleveland
Source: ClinicalTrials.gov · NCT07738978 · last updated 2026-07-31