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RecruitingChronic Low-back Pain

Algorithm-informed Decision-making to Advance Pain Treatment

Eligible age

25+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

Researchers are exploring how certain personal factors, such as symptoms, health history, and lifestyle, may help predict which treatments will work best for someone. The purpose of this study is to evaluate how well a study algorithm chooses the best treatments for a patient when considering their unique pain characteristics.

Sponsor: University of Michigan

You may qualify if…

  • ✓ Participants must meet the definition of Chronic Low Back Pain (cLBP) described in the NIH Task Force Report on Research Standards for cLBP, i.e., low back pain present at least six months, and present more than half of those days.2
  • ✓ Individuals must have a pain interference score of ≥60 on PROMIS Pain Interference. The normal population mean for pain interference is 50. Participants must be 1 standard deviation (SD) above the population mean (\>=60) for inclusion.
  • ✓ Individuals must be willing and eligible to receive at least three of the four proposed interventions.
  • ✓ Able to stand for at least 10 minutes

You may not qualify if…

  • ✕ Red flags suggesting the presence of an identifiable cause of low back pain, including fever, weight loss, initiation of pain following major trauma, immunosuppression, IV drug use, recent bacterial infection, severe or persistent sensory or motor involvement of bowel, bladder, or lower extremity.
  • ✕ Unable to read, write of speak fluent English
  • ✕ Visual or hearing difficulties that would preclude participation
  • ✕ Active uncontrolled drug/alcohol addiction
  • ✕ Individuals receiving new disability or compensation or involved in litigation in the past 12 months.
  • ✕ Pregnancy or breastfeeding
  • ✕ Individuals on high doses of opioids (over 100 Oral Morphine Equivalents \[OME\] per day).
  • ✕ Upcoming scheduled back surgery, back surgery within the last year, or more than one back surgery in the past.

Where it's recruiting

Michigan

Ann Arbor

Source: ClinicalTrials.gov · NCT07731750 · last updated 2026-09-15

Algorithm-informed Decision-making to Advance Pain Treatment · TrialPath