Hydration & Female Life Stages
Eligible age
18–60 yrs
Accepts
Women
Locations
2 states
Healthy volunteers
Yes
See if you qualify for this study
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About this study
Female life stages including premenopausal, perimenopausal, postmenopausal, are characterized by changing concentrations and patterns of hormones. The premenopause stage represents the reproductive years with normal menstrual cycles lasting between 21-35 days. The perimenopause stage is the beginning of the menopause transition and can last up to 10 years. During this transition, menstrual cycles become longer and irregular in length (7 days or longer). After 12 consecutive months with no period, the transition is complete into the postmenopause stage. Hormones that change across the lifespan are known to influence systems that regulate thirst, fluid balance, and sodium balance. Yet, fluid balance across life stages remains poorly understood, with no direct comparisons across all three life stages. The purpose of this study is to evaluate the effect of female life stage on rehydration with water and electrolyte solution after overnight fast and fluid restriction
Sponsor: PepsiCo Global R&D
You may qualify if…
- ✓ • Sex assigned female at birth.
- ✓ Recreationally active (engaged in light to moderate-intensity, intermittent, or steady-state exercise at least 3 days per week for at least 30 min at a time)
- ✓ Age 18-60 years, within the following life stage ranges specified below:
- ✓ Premenopausal:
- ✓ 18-35 years
- ✓ Self-report regular spontaneous menstrual cycle length (21-35 days) for the past 2 menstrual cycles
- ✓ Menstrual cycle length \< 7 days variation in consecutive cycles
- ✓ Perimenopausal:
You may not qualify if…
- ✕ • Currently pregnant or breastfeeding
- ✕ \< 6 months since giving birth (even if experiencing 2 regular menstrual cycles in a row)
- ✕ Smoking within the last 5 years
- ✕ History of adverse events (e.g., fainting) with blood draws
- ✕ Participants with large amount of internal metal (e.g., spinal rod) will be excluded from the DXA scan only (Brandenton)
- ✕ Participant has participated in a clinical trial within the past 30 days
- ✕ Participant has participated in any PepsiCo trial within past 3 months
- ✕ Participant has a condition or is taking medication that the investigator believes would interfere with his/her ability to provide informed consent, comply with the study protocol, which might confound the interpretation of the study results, or put the person at undue risk
Where it's recruiting
Source: ClinicalTrials.gov · NCT07653620 · last updated 2026-06-17