RecruitingMenopause

MenoZen VR for Menopause Symptom Management

Eligible age

45–60 yrs

Accepts

Women

Locations

1 state

Healthy volunteers

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About this study

The purpose of this research is to evaluate the feasibility, acceptability, tolerability, and clinical efficacy of MenoZen VR (virtual reality) for managing menopause symptoms in women.

Sponsor: Mayo Clinic

You may qualify if…

✓ Women currently between 45-60 years of age;
✓ Have moderate to severe VMS, defined as 28 or more hot flashes per week (including night sweats) and were sufficient severity to prompt them to seek therapeutic intervention;
✓ Are English-speaking;
✓ Able to participate fully in all aspects of the study;
✓ Have understood and signed study informed consent;
✓ Have access to a computer or smartphone and home Wi-Fi;
✓ Willing to participate in weekly VR sessions for 8 weeks.

You may not qualify if…

✕ Women receiving systemic menopause hormonal therapy (progesterone, testosterone, estrogen). Low-dose topical vaginal estrogen is okay;
✕ Women receiving non-hormonal therapy for the management of hot flashes (fezolinetant or elinzanetant, any SSRI/SNRI, oxybytunin, and/or gabapentin being prescribed for hot flashes, if for other reasons and still with hot flashes then okay);
✕ Women receiving active cognitive behavioral therapy (CBT) for hot flashes. CBT for mood symptoms is okay;
✕ Have a known, active, untreated clinically significant psychiatric condition (severe depression, psychosis, bipolar disorder, or severe depression);
✕ Have severe visual, auditory, or vestibular impairments that may interfere with VR use;
✕ Have a facial/head deformity that will prohibit the wearing of a VR head mounted displace (HMD);
✕ Self-reported history of acute and/or severe motion sickness;
✕ Have had a seizure in the past year;

Where it's recruiting

Florida

Jacksonville

Source: ClinicalTrials.gov · NCT07633743 · last updated 2026-09-24