RecruitingDiabetes Mellitus, Type 2
A Trial Evaluating AMG 127 in Healthy Participants and Participants With Type 2 Diabetes Mellitus
Eligible age
18–75 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
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About this study
The main objective of this trial is to assess the safety and tolerability of AMG 127 as single dose and multiple doses in healthy participants and participants with type 2 diabetes mellitus (T2DM).
Sponsor: Amgen
You may qualify if…
- ✓ Participant must be 18-65 years of age
- ✓ Participant must be overtly healthy
- ✓ Participant must be 40-75 years of age
- ✓ Confirmed diagnoses of T2DM
You may not qualify if…
- ✕ History of hypotension, syncope, or orthostatic intolerance
- ✕ Systolic blood pressure \>140 millimeters of mercury (mmHg) or diastolic blood pressure \>90 mmHg
- ✕ Hemoglobin A1c (HbA1c) \>10% within the last 3 months
- ✕ History of hypotension, syncope, or orthostatic intolerance
- ✕ Systolic blood pressure \>160 mmHg or diastolic blood pressure \>100 mmHg
Where it's recruiting
Florida
Aventura
Source: ClinicalTrials.gov · NCT07590193 · last updated 2026-06-23