RecruitingSpinal Cord Injuries (SCI)
Spasticity in SCI Following Acute Intermittent Hypoxia
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
This study aims to observe the effects of administration of a breathing intervention (Acute Intermittent Hypoxia (AIH)) on spasticity (tightness) in individuals with incomplete Spinal Cord Injury. It is hypothesized that hypoxia will decrease the reflex threshold of the biceps brachii, indicating an increase in spasticity following the AIH.
Sponsor: Zev Rymer
You may qualify if…
- ✓ Age \>= 18
- ✓ Non-progressive spinal Cord injury at least 6 months prior
- ✓ Level of injury between C1-C8
- ✓ ISNCSCI ASIA classification C or D
- ✓ Measurable Spasticity
You may not qualify if…
- ✕ Pre-existing hypoxic pulmonary disease
- ✕ Positive Covid-Pneumonia diagnosis within 1 year of visit
- ✕ Uncontrolled hypertension \>140/90 mmHg
- ✕ Individuals who are currently pregnant/nursing or planning on becoming pregnant
- ✕ Individuals with a tracheostomy or who utilize mechanical ventilation
- ✕ A botulinum toxin injection to upper extremity musculature within the past 3 months
- ✕ Currently taking Baclofen
- ✕ Congestive Heart Failure
Where it's recruiting
Illinois
Chicago
Source: ClinicalTrials.gov · NCT07583498 · last updated 2026-05-13