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RecruitingMild Cognitive Impairment (MCI)

Safety And Tolerability Of Gamma Glutamylcysteine (GGC) Oral Supplementation In MCI Patients

Eligible age

55–80 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The goal of this study is to evaluate the safety and tolerability of Gamma Glutamylcysteine (GGC) supplement at different doses (400mg/day or 800mg/day or 1200mg/day) when administered orally to patients with MCI over 3 months. This study is designed to generate preliminary clinical safety data to inform the feasibility and design of larger controlled trials.

Sponsor: Pravat Mandal

You may qualify if…

  • 1. Memory complaints;
  • 2. MCI diagnosis
  • 3. MoCA score between 18-25
  • 4. Age 55 - 80 years old.
  • 5. Ability to read and write in English

You may not qualify if…

  • 1. Subjects with acute head trauma or head injury involving loss of consciousness;
  • 2. Subjects with a history of cancer;
  • 3. Subjects with a history of schizophrenia, manic-depressive disorder
  • 4. Subjects on antioxidant therapy (ashwagandha, gingko biloba, N-acetylcysteine or glutathione)
  • 5. Subjects on illicit drug (cocaine, heroin, marijuana, or fentanyl) abuse/dependence;

Where it's recruiting

Pennsylvania

Pittsburgh

Source: ClinicalTrials.gov · NCT07583251 · last updated 2026-06-03