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RecruitingPARKINSON DISEASE (Disorder)

Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

Eligible age

18–80 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The purpose of this study is to find out whether a type of gentle nerve stimulation, called transcutaneous auricular Vagus Nerve Stimulation (taVNS), can help improve how the body regulates heart rate and blood pressure in people with Parkinson's Disease (PD). Problems with heart rate and blood pressure control are common and can make it harder for people to exercise or do daily activities. By using this non-invasive form of nerve stimulation and testing how it affects the body's natural responses, this study hopes to learn if taVNS could be a helpful tool to support physical therapy and improve overall function.

Sponsor: University of Alabama at Birmingham

You may qualify if…

  • ✓ Diagnosis of idiopathic PD
  • ✓ Stable medication for at least 4 weeks prior to the study

You may not qualify if…

  • ✕ Use of beta blockers
  • ✕ Sustained severe hypertension (\>/= 180/110 mmHg while seated)
  • ✕ Significant uncontrolled cardiac arrhythmia
  • ✕ Unstable angina
  • ✕ Congestive heart failure
  • ✕ History of myocardial infarction
  • ✕ History of seizures
  • ✕ Severe cognitive impairment

Where it's recruiting

Alabama

Birmingham

Source: ClinicalTrials.gov · NCT07557706 · last updated 2026-06-18

Using taVNS to Modulate Cardiovascular Function in Individuals With Ne · TrialPath