RecruitingAbnormal Uterine Bleeding (AUB)Endometrial CancerAtypical Endometrial Hyperplasia
Endometrial Cancer Vaginal Fluid Specimen Collection Study
Eligible age
18+ yrs
Accepts
Women
Locations
1 state
Healthy volunteers
No
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About this study
This is a multicenter, prospective, specimen collection study for development and evaluation of tests used to detect endometrial cancer, other cancers, or their causes.
Sponsor: Exact Sciences Corporation
You may qualify if…
- ✓ Cohort 1 Participants:
- ✓ Age ≥ 45 years, OR age ≥ 18 years with at least one risk factor
- ✓ Diagnosed with abnormal uterine bleeding (AUB)
- ✓ Planning standard-of-care endometrial tissue sampling to assess for endometrial cancer (EC) or atypical endometrial hyperplasia/endometrial intraepithelial neoplasia (AEH/EIN)
- ✓ Cohort 2 Participants:
- ✓ Age ≥ 18 years
- ✓ Newly diagnosed, biopsy-confirmed EC or AEH/EIN
- ✓ Planning initial management for their endometrial pathology
You may not qualify if…
- ✕ Prior partial or complete hysterectomy
- ✕ Current pregnancy
- ✕ Prior pelvic or vaginal radiotherapy
- ✕ Chemotherapy within past 5 years (except tamoxifen)
- ✕ Any condition judged by the Investigator to preclude participation
- ✕ Additional for Cohort 1:
- ✕ Cancer diagnosis within past 5 years (except non-gynecologic skin cancer)
- ✕ Current biopsy-proven cervical, vaginal, or vulvar cancer, or lower genital tract dysplasia
Where it's recruiting
Tennessee
Murfreesboro
Source: ClinicalTrials.gov · NCT07544680 · last updated 2026-04-22