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RecruitingMild Cognitive ImpairmentDementiaBPSD

Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD

Eligible age

65+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The purpose of this study is to test the usefulness and the effect of Smart Virtual Reminiscence (SVR) therapy intervention on the Behavioral and Psychological Symptoms of Dementia (BPSD) of patients with Alzheimer's Disease and Related Dementias (ADRD). SVR is designed to help older adults improve their psychological well-being and cognition. This research supports our long-term goal of designing and implementing intelligent interactive systems to improve the health of individuals with ADRD.

Sponsor: Indiana University

You may qualify if…

  • age ≥ 65 years
  • diagnosis of MCI (mild cognitive impairment) or mild ADRD
  • access to a reliable internet connection
  • community-dwelling
  • elevated behavioral and psychological symptoms of dementia (BPSD), indicated by a HABC (Healthy Aging Brain Care) monitor score above 14 on caregiver report or self report (indicating elevated levels of BPSD)
  • presence of one or more specific BPSD behaviors (e.g., agitation, anxiety, depression, apathy, or sleep disturbances)
  • ability to consent for themselves.
  • ≥ 21 years old

You may not qualify if…

  • lives in an assisted living facility or nursing home
  • has moderate to severe ADRD as measured by the Quick Dementia Rating System
  • has a life expectancy of less than 6 months.
  • For the care partner:
  • has MCI or dementia
  • has a severe mental illness or substance abuse
  • has a life expectancy of less than 6 months.

Where it's recruiting

Indiana

Indianapolis

Source: ClinicalTrials.gov · NCT07499570 · last updated 2026-05-06

Multi-modal Large Language Model-Empowered Talk Therapy for Older Adul · TrialPath