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RecruitingObesityOverweight

Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity

Eligible age

18–75 yrs

Accepts

All genders

Locations

14 states

Healthy volunteers

No

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About this study

The primary objective of this study is to determine the efficacy of oral KAI-7535 once daily compared with placebo on percent change in body weight in participants living with obesity or overweight, with at least 1 weight-related comorbidity, without diabetes mellitus. Efficacy in participants with type 2 diabetes mellitus will be evaluated. Safety and tolerability and other weight-related outcomes will be evaluated in both types of participants.

Sponsor: Kailera

Where it's recruiting

Arizona

Chandler · Phoenix

California

Irvine · Lincoln · Northridge

Florida

Jacksonville · Jupiter · Palm Springs · Pembroke Pines

Georgia

Decatur

Illinois

Chicago · Skokie

Indiana

South Bend

Louisiana

Kenner

Michigan

Garden City

Missouri

Jefferson City · Kansas City

South Carolina

Spartanburg

Tennessee

Knoxville

Source: ClinicalTrials.gov · NCT07497880 · last updated 2026-07-28