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RecruitingMacular DegenerationAge-Related Macular DegenerationChoroidal Neovascularization

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

Eligible age

50+ yrs

Accepts

All genders

Locations

25 states

Healthy volunteers

No

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About this study

Researchers are looking for new ways to treat neovascular age-related macular degeneration (NVAMD). Available standard (usual) treatments for NVAMD, such as aflibercept, may not work for every person. Researchers want to learn if a trial medicine called tiespectus (also called MK-8748 or EYE201) can treat NVAMD. The goal of this trial is to learn if tiespectus works as well as aflibercept to treat NVAMD.

Sponsor: EyeBiotech Ltd.

Where it's recruiting

Arizona

Gilbert

California

Encino · Mountain View · Santa Ana

Colorado

Colorado Springs · Denver · Pueblo

Connecticut

Danbury · Manchester · Waterford

Florida

Fort Myers · Orlando · Sarasota · Winter Haven

Illinois

Joliet · Lemont

Iowa

West Des Moines

Kansas

Lenexa

Kentucky

Louisville

Maine

Portland

Maryland

Hagerstown

Massachusetts

Springfield

Source: ClinicalTrials.gov · NCT07496567 · last updated 2026-08-06

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration · TrialPath