Fasted vs. Fed State Exercise
Eligible age
18–59 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
Although many medications exist for both heart disease and obesity, cost, lack of access for all people, side effects and the desire for a more natural solution have left many people seeking lifestyle treatments such as exercise. Scientists know that exercise is highly beneficial for heart health. When exercise also produces weight loss, these benefits are much improved. Although using exercise to treat or prevent heart disease / obesity is recommended, not all people respond well. Some see significant weight loss and health improvements while others see little changes. For these reasons, new strategies surrounding the use and design of an exercise program are needed. One such strategy could be performing aerobic exercise before breakfast (fasted exercise). When exercising fasted, food/energy stores are low, and one relies on stored body fat for energy. This may help heart health and weight loss. This has never been tested in a program long enough to see such changes. This study will, for the first time, assess the effects of a 16-week aerobic exercise program performed fasted compared to after eating. Outcomes will include blood fats, blood pressure, fat-burning abilities and weight loss. Starting an exercise program can also make people to eat more. This limits the success of exercise. The study will also evaluate ways fasted exercise could change eating, as it possible that fasted exercise could also cause people to eat more, which would limit weight loss and health improvements.
Sponsor: Arkansas Colleges of Health Education
You may qualify if…
- ✓ Aged 18-59
- ✓ BMI 25-45
- ✓ Healthy enough to exercise
You may not qualify if…
- ✕ Taking medications or supplements that are known to influence energy expenditure,
- ✕ Currently exercising more than once per week
- ✕ Currently dieting for weight loss
- ✕ Currently taking weight loss drugs
- ✕ Have had a previous weight loss surgery
- ✕ Currently diagnosed with Diabetes
- ✕ Currently diagnosed with heart disease (Heart failure, uncontrolled hypertension, uncontrolled hypercholesterolemia, Coronary heart disease)
Where it's recruiting
Fort Smith
Source: ClinicalTrials.gov · NCT07487090 · last updated 2026-03-23