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RecruitingPrion Disease

PrP-targeting siRNA Safety & Mechanism Study

Eligible age

18+ yrs

Accepts

All genders

Locations

5 states

Healthy volunteers

No

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About this study

The purpose of this trial is to evaluate safety, tolerability, pharmacokinetics and pharmacodynamic impact of PrP-siRNA in symptomatic prion disease patients.

Sponsor: Broad Institute of MIT and Harvard

Where it's recruiting

Minnesota

Rochester

New York

New York

Ohio

Cleveland

Tennessee

Nashville

Source: ClinicalTrials.gov · NCT07444580 · last updated 2026-06-05