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RecruitingMild Cognitive Impairment (MCI)Parkinsons Disease (PD)Healthy Adult

Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations

Eligible age

18–65 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

This study plans to learn more about how stimulating the vagus nerve through gentle electrical stimulation applied to the ear can affect decision-making, problem-solving, and other thinking abilities. This process, called transcutaneous auricular vagus nerve stimulation (taVNS), could help improve brain function in both healthy individuals and people with Parkinson's disease (PD).

Sponsor: University of Colorado, Denver

You may qualify if…

  • 1. Individuals aged 18-65.
  • 2. Ability to sign informed consent.
  • 3. Ability to follow written and verbal instructions.
  • 4. For the PD group, a clinical diagnosis of Parkinson's disease without severe motor or cognitive impairments.

You may not qualify if…

  • 1. Current uncontrolled and/or clinically significant medical condition.
  • 2. Abnormal ear anatomy or active ear infection.
  • 3. Electronic medical implants, such as pacemakers, cochlear prosthesis, neuro-stimulators.
  • 4. Uncorrected visual impairments that would interfere with task performance.
  • (6) Other significant diseases or disorders that might impair study participation.

Where it's recruiting

Colorado

Aurora

Source: ClinicalTrials.gov · NCT07424365 · last updated 2026-02-20

Study to Investigate Vagus Nerve Stimulation to Augment Executive Func · TrialPath