RecruitingType2diabetesMild Cognitive ImpairmentAge-related Cognitive Decline
Feasibility and Adherence to a Technology-assisted Home-based Strength Training Program in Adults With Type 2 Diabetes Mellitus and Mild Cognitive Impairment
Eligible age
55–80 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
This is a single-arm feasibility study employing a pre-post design with a 12-week intervention period. The study utilizes a telehealth-assisted home-based resistance exercise program, with a structured progression from supervised to unsupervised sessions over 12 weeks.
Sponsor: The University of Texas Medical Branch, Galveston
You may qualify if…
- ✓ 1. Age: 55-80 years
- ✓ 2. Diabetes: Diagnosed T2DM with ≥5 years duration
- ✓ 3. Cognitive Status: Mild cognitive impairment as defined by Petersen criteria and confirmed by Montreal Cognitive Assessment (MoCA) scores of 18-25
- ✓ 4. Medication Stability: Stable medication regimen for at least 3 months
- ✓ 5. Physical Capability: Physically capable of participating in moderate-intensity exercise (physician clearance required)
- ✓ 6. Support System: Having a caregiver or support person willing to assist with technology use if needed
You may not qualify if…
- ✕ 1. Diagnosis of movement disorders such as multiple sclerosis, parkinson's disease
- ✕ 2. Diagnosis of Alzheimer's disease,
- ✕ 3. Current diagnosis of severe depression, major psychiatric conditions such as bipolar disorder, psychosis, schizophrenia, or alcoholism that could affect the ability to understand and/or cooperate fully with the protocol.
- ✕ 4. Significant cerebral vascular disease
- ✕ 5. Concomitant medications with significant cholinergic or anticholinergic effects or adverse effects on cognition, including antipsychotics, tricyclic antidepressants, anticonvulsants, sedative/hypnotics, anxiolytics, glucocorticoids (chronic or frequent intermittent),
- ✕ 6. Visual/hearing impairment that would significantly impact the ability to participate in psychometric testing.
- ✕ 7. Significant medical illness or organ failure, including hepatic or renal failure, unstable cardiac disease,
- ✕ 8. Untreated B12 deficiency or hypothyroidism (stable treatment for at least 3 months is allowable).
Where it's recruiting
Texas
Galveston
Source: ClinicalTrials.gov · NCT07416799 · last updated 2026-05-11