Effects of Amylopectin Chromium Blend on Whole-Body Protein Kinetics and Glucose in Peri/Post-Menopausal Women
Eligible age
40–70 yrs
Accepts
Women
Locations
1 state
Healthy volunteers
Yes
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About this study
The goal of this study is to better understand how an amylopectin chromium blend may influence whole body protein balance in women during midlife, when hormonal changes can adversely affect protein metabolism and muscle maintenance. Continuous glucose monitoring will also be used to assess glycemic control over a 24-hour period. The main questions the study aims to answer are: * Does the use of an amylopectin chromium blend in peri- and post-menopausal women help to support positive protein balance * Can the affect be achieved using a concentrated dose Researchers will compare the nutritional supplement to a placebo (amylopectin alone) to see if the amylopectin chromium blend can promote positive protein balance. A concentrated dose of the supplement will also be evaluated for comparative effectiveness. Participants will: * Consume the nutritional supplement (standard or concentrated dose) or placebo acutely after a short resistance exercise bout * Complete four in-person visits, including the single-day intervention Results from this research may help guide future nutritional strategies to support healthy aging, muscle function, and overall metabolic health.
Sponsor: Nutrition 21, Inc.
You may qualify if…
- ✓ Women aged 40-65 years who meet either of the following menstrual-history criteria:
- ✓ ≥ 60 days but \< 12 months of amenorrhea (late perimenopause)
- ✓ Women with ≥ 12 months of spontaneous amenorrhea (post-menopausal)
- ✓ No more than 3 days per week of structured physical activity
- ✓ Provide voluntary signed and dated informed consent.
- ✓ Be in good health and able to participate in an exercise bout as determined by assessment, medical history, and routine blood chemistries.
- ✓ Between the of 40 and 65 years of age (inclusive).
- ✓ Body Mass Index of 18.5-34.9 (inclusive).
You may not qualify if…
- ✕ Current use of any dietary ingredient that impacts glucose control or insulin sensitivity.
- ✕ Current vegans or vegetarians.
- ✕ Intolerance to dairy foods/drinks.
- ✕ Smokes more than 10 cigarettes per day or uses other nicotine products (i.e. vape, patch) that deliver a similar amount of nicotine.
- ✕ History of malignancy in the previous 5 years except for non-melanoma skin cancer (basal cell cancer or squamous cell cancer of the skin).
- ✕ Prior gastrointestinal bypass surgery (Lapband, etc.).
- ✕ Individuals using any kind of GLP-1 medications.
- ✕ Other known gastrointestinal or metabolic diseases that might impact nutrient absorption or metabolism, e.g. electrolyte abnormalities, diabetes, thyroid disease, adrenal disease, hypogonadism, short bowel syndrome, diarrheal illnesses, history of colon resection, gastric ulcer, reflux disease, gastroparesis, Inborn-Errors-of-Metabolism (such as PKU).
Where it's recruiting
Canfield
Source: ClinicalTrials.gov · NCT07402382 · last updated 2026-04-13