Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients
Eligible age
18–65 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
The goal of this study is to determine whether a multimodal sleep pathway can enhance sleep quality in hospitalized patients with orthopedic trauma. It will also evaluate the effect of this pathway on opioid use and pain perception during recovery. The main study questions are: * Does the multimodal sleep pathway improve sleep quality and duration? * Does the pathway reduce the amount of opioids patients use during hospitalization? * Does improved sleep reduce pain interference with daily activities? Researchers will compare the multimodal sleep pathway to standard postoperative care to see if the pathway helps patients sleep better and rely less on opioids. Participants will: * Receive either the multimodal sleep pathway (zolpidem, melatonin, and sleep hygiene education) or standard care * Wear a wrist-worn actigraphy device to track sleep during their hospital stay * Complete daily questionnaires about sleep quality and pain
Sponsor: Emory University
You may qualify if…
- ✓ Hospitalized with an isolated lower extremity orthopedic injury requiring surgical intervention.
- ✓ Expected hospital stay of at least 3 days.
- ✓ No known pre-existing sleep disorders.
- ✓ No current use of sleep aids, such as zolpidem or melatonin, before hospitalization
You may not qualify if…
- ✕ Participants with a history of chronic opioid use prior to hospitalization.
- ✕ Pre-existing diagnosed sleep disorders (e.g., obstructive sleep apnea, insomnia).
- ✕ Contraindications to zolpidem or melatonin use (e.g., allergies, interactions with other medications).
- ✕ Cognitive impairment or inability to comply with study procedures.
- ✕ Severe traumatic brain injury or other neurological conditions that may affect sleep or pain perception.
- ✕ Participants receiving mechanical ventilation or sedatives that significantly affect sleep architecture.
Where it's recruiting
Atlanta
Source: ClinicalTrials.gov · NCT07336277 · last updated 2026-07-30