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RecruitingObstructive Sleep Apnea (OSA)Traumatic Brain Injury (TBI)

Low-Tech Treatments for Obstructive Sleep Apnea

Eligible age

18–65 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The overall purpose of this study is to compare changes in sleep outcomes in people with obstructive sleep apnea (OSA) depending on their participation in one of two behavioral interventions; both involve drinking water and breathing. A second purpose is to compare outcomes between people who have sustained a traumatic brain injury (TBI) and those with no history of TBI. The main questions it aims to answer are whether sleep quality improves after 3-months of high-resistance versus low-resistance exercises, and whether people have different outcomes depending on their history of TBI.

Sponsor: Uniformed Services University of the Health Sciences

You may qualify if…

  • New diagnosis of OSA (AHI, ≥ 5) or failure of first-line OSA treatment;
  • Willingness to forego first-line OSA treatment or stop current OSA treatment for 3 months;
  • Ability to follow directions and perform the required exercises;
  • Age between 18-65 yr.

You may not qualify if…

  • Current use of OSA treatment;
  • Medical comorbidities that require restricting fluid intake (e.g., dysphagia, renal disease, liver disease, hyponatremia);
  • Severe nasal obstruction; 4) severe ankyloglossia; 4) craniofacial abnormality; 5) severe pulmonary disease; 6) severe post-traumatic stress disorder; 7) very severe insomnia; 8) body mass index (BMI) ≥30 kg/m2

Where it's recruiting

Maryland

Bethesda

Source: ClinicalTrials.gov · NCT07301710 · last updated 2026-02-17

Low-Tech Treatments for Obstructive Sleep Apnea · TrialPath