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RecruitingHepatocellular Carcinoma (HCC)

A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)

Eligible age

18+ yrs

Accepts

All genders

Locations

7 states

Healthy volunteers

No

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About this study

The purpose of this study is to evaluate the safety and tolerability of Pumitamig alone or in combination with Ipilimumab in participants with first-line advanced or unresectable Hepatocellular Carcinoma (HCC)

Sponsor: Bristol-Myers Squibb

You may qualify if…

  • Participants must have a histologically confirmed diagnosis of locally advanced or unresectable Hepatocellular Carcinoma (HCC).
  • Participants must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.
  • Participants must have no prior systemic therapy for advanced/ unresectable HCC.
  • Participants must have measurable disease as per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1.

You may not qualify if…

  • Participants must not have significant bleeding or coagulation disorders or other obvious bleeding risk evidence.
  • Participants must not have an organ transplant or autoimmune disease.
  • Other protocol-defined Inclusion/Exclusion criteria apply.

Where it's recruiting

California

Los Angeles

Illinois

Chicago

New Jersey

Hackensack

New York

Mineola

Oregon

Portland

Tennessee

Nashville

Washington

Seattle

Source: ClinicalTrials.gov · NCT07291076 · last updated 2026-06-02