RecruitingFibrin Blood ClotPregnancyPregnancy Complicated by Cardiovascular Disorders as Postpartum Condition, Delivered During Previous Episode
Pregnancy and Fibrin Clot Properties
Eligible age
18–40 yrs
Accepts
Women
Locations
0 states
Healthy volunteers
Yes
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About this study
1. The structure of fibrin clot and thrombin generation may vary between trimesters of pregnancy. 2. Unfavorably altered fibrin clot properties along with enhanced thrombin generation may lead to the development of complications during pregnancy such as TE and hypertensive disorders. 3. The application of machine learning techniques may help to identify previously undetected phenotypes with increased risk of TE and hypertensive disorders during pregnancy.
Sponsor: Jagiellonian University
You may qualify if…
- ✓ I. age 18-40 years; II. natural conception (without assisted reproductive techniques).
You may not qualify if…
- ✕ I. use of hormonal therapy (i.e., oral contraceptives, progestogens) within 3 months before or during pregnancy; II. use of anticoagulants oral/subcutaneous within 3 months before or during pregnancy; III. increased risk factors of VTE (i.e., obesity - body mass index \>30 kg/m2; smoking) or history of VTE; IV. Concomitant diseases, i.e: severe hypertension, diabetes mellitus, autoimmune diseases (i.e., systemic lupus erythematosus, antiphospholipid syndrome); V. congenital or acquired thrombophilia (i.e., mutation factor V Leiden, prothrombin mutation).
Source: ClinicalTrials.gov · NCT07275476 · last updated 2025-12-10