RecruitingDiabetes Mellitus, Type 2
A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006)
Eligible age
18–75 yrs
Accepts
All genders
Locations
3 states
Healthy volunteers
No
See if you qualify for this study
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About this study
The purpose of this study is to learn about the safety and if people tolerate a study medicine called MK-1403. The study will also measure what happens to MK-1403 in the body of a person with type 2 diabetes (T2D) over time (pharmacokinetic or PK study), and how it affects the amount of high-sensitivity C-reactive protein (hsCRP) in a person's blood.
Sponsor: Merck Sharp & Dohme LLC
You may qualify if…
- ✓ Has a confirmed diagnosis of Type 2 diabetes mellitus (T2DM)
- ✓ Has body mass index (BMI) between 18 and 40 kg/m\^2, inclusive
You may not qualify if…
- ✕ Has Type 1 diabetes mellitus or secondary types of diabetes
- ✕ Has a history of congestive heart failure (New York Heart Association \[NYHA\] Class 3 or 4)
- ✕ Has history of myocardial infarction, uncontrolled arrhythmias, cardiac revascularization, angina, unstable peripheral arterial disease and/or stroke
- ✕ Has history of cancer (malignancy)
- ✕ Has positive test(s) for hepatitis B surface antigen (HBsAg), hepatitis C antibodies, or human immunodeficiency virus (HIV)
- ✕ Has a history of gastrointestinal (GI) disease which might affect food and drug absorption, or has had gastric bypass or similar surgery
Where it's recruiting
Source: ClinicalTrials.gov · NCT07242469 · last updated 2026-07-31