Endothelial Dysfunction After SCI
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
This study plans to learn how endothelial cells, single cell lining of blood vessels may be dysfunctional after a spinal cord injury. Endothelial dysfunction will be measured by the capacity of blood vessels to vasodilate (increase in size) and alter blood flow is lower in adults with a spinal cord injury in comparison to adults without a spinal cord injury. The mechanisms which may alter this function may be critical in reducing the risk of heart attacks and strokes in people with spinal cord injuries.
Sponsor: Craig Hospital
You may not qualify if…
- ✕ Overt chronic diseases as assessed by: a) clinically documented medical history; b) physical examination; c) blood pressure and ECG at rest; and d) complete blood chemistries and hematological evaluation.
- ✕ Active infection
- ✕ Recent (\< 3 months) surgery
- ✕ Current smoking history (within past 12 months)
- ✕ Report more than low-risk alcohol consumption
- ✕ History of drug abuse
- ✕ Currently taking cardiovascular (statins, beta-blockers) therapeutics and/or other medications that could influence the outcome measures
Where it's recruiting
Englewood
Source: ClinicalTrials.gov · NCT07227727 · last updated 2025-11-14