RecruitingObstructive Sleep ApneaPremature Ventricular Contraction (PVC)Atrial Fibrillation (AF)
Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation
Eligible age
21+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
Whereas the available evidence mostly supports chronic sleep disruption as a risk factor for incident AF, less is known about the near-term risk of a discrete atrial fibrillation (AF) episode following a night of disrupted or poor-quality sleep. This prospective, randomized, case-crossover study aims to examine the acute effects of sleep disruption on clinically relevant cardiac ectopy pertinent to AF.
Sponsor: University of California, San Francisco
You may qualify if…
- ✓ Are age 21 years or older
- ✓ Have a HGNS device implanted for obstructive sleep apnea and followed up at UCSF Health
- ✓ Are willing to abstain from using the upper airway stimulation device for no more than two consecutive days as instructed over the 14-day trial period
- ✓ Able and willing to provide written informed consent
You may not qualify if…
- ✕ Currently pregnant or trying to get pregnant
- ✕ Are currently taking class 1 or 3 anti-arrhythmic medications
- ✕ Have a history of permanent AF or expected to have continuous AF throughout the study period
- ✕ Have congenital heart disease
- ✕ Ventricular pacing \>40%
- ✕ Are unable to read or sign to provide informed consent
Where it's recruiting
California
San Francisco
Source: ClinicalTrials.gov · NCT07220525 · last updated 2026-01-23