RecruitingAcute Neurological InjuryAcute Medical Conditions
Transcutaneous Auricular Vagus Enhanced Recovery in the NeuroICU
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
This study will demonstrate the impact of taVNS on reducing adverse events in NeuroICU patients, determine if taVNS reduces length of stay, and quantify the economic benefits of taVNS implementation in a broader neurocritical care population.
Sponsor: Washington University School of Medicine
You may qualify if…
- ✓ Age ≥18
- ✓ Admission to the NeuroICU within 36 hours of onset of an acute medical condition.
- ✓ Patient or authorized legal representative should be able to provide consent within 36 hours of ICU arrival
- ✓ Presence of at least one predictor of critical illness and/or severe brain / spinal cord injury:
- ✓ Glasgow Coma Scale GCS \>3 \& \<= 12 at admission
- ✓ NIH stroke scale of 6 or greater
- ✓ Requirement for ongoing mechanical ventilation
- ✓ Requirement for ongoing vasopressor support
You may not qualify if…
- ✕ Systemic immunosuppression
- ✕ Receiving ongoing cancer therapy
- ✕ Implanted electrical device (e.g., pacemaker, stimulator)
- ✕ Bradycardia on admission (Sustained bradycardia on arrival with a heart rate \< 50 bpm for \>5 minutes)
- ✕ Risk of imminent death or limitation of care (e.g., Glasgow Coma Scale of 3, pupillary dilatation)
- ✕ Expected ICU stay of less than 72 hours, as determined by attending physician or ICU fellow
- ✕ Pregnancy
- ✕ COVID-19
Where it's recruiting
Missouri
St Louis
Source: ClinicalTrials.gov · NCT07219108 · last updated 2025-10-21