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RecruitingOsteoarthritis HandOsteoarthritis Wrist

Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis

Eligible age

50+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The purpose of this research is to compare low-dose radiotherapy to corticosteroid injection for treatment of hand/wrist osteoarthritis.

Sponsor: Mayo Clinic

You may qualify if…

  • Patient at Mayo Clinic, Rochester, MN
  • Age 50 years or older
  • Mild, moderate, or severe hand OA (Kellgren and Lawrence classification grade 2, 3, or 4) on hand radiographs within the last 24 months
  • Hand OA pain with a minimum VAS score relating to hand pain of ≥40 (on a 100-point scale) when using the affected hand
  • Ability to complete study questionnaires

You may not qualify if…

  • History of previous surgery to the affected hand(s)
  • Autoimmune joint disease such as rheumatoid arthritis or psoriatic arthritis
  • Active confounding hand condition such as stenosing tenosynovitis or Dupuytren's contracture
  • Recent injury (within last 1 month) to the affected hand causing current pain
  • History of crystalline arthritis (gout or pseudogout) flare in the affected hand(s)
  • Active use of opioid pain medication(s) or oral steroids within the last 3 months
  • Fibromyalgia or central sensitization syndrome
  • Hand CSI or other hand injection within the past 3 months

Where it's recruiting

Minnesota

Rochester

Source: ClinicalTrials.gov · NCT07217405 · last updated 2026-04-24