Massage: Neuroimaging and Correlates of Response - 6-week Study
Eligible age
18–64 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
This study will help find out if massage and touch therapies change brain activity and reduce the symptoms of anxiety. Massage therapy has well known health benefits. This study will help to learn if these therapies reduce the symptoms of anxiety by changing brain activity. Participation in the study will last about 8 weeks. This is a randomized research study. "Randomized" means that participants will be assigned to a study group by chance, like flipping a coin. Participants will be randomized into one of two study groups, and will have an equal chance of being placed in one of the groups: - Swedish massage therapy twice per week for 6 weeks - Light touch therapy twice per week for 6 weeks At each study, the study staff ask about life stressors, medical health, medicine use, and illicit substance use over the past week. The study uses magnetic resonance imaging (MRI) as well as functional MRI (fMRI) to look at the structure and activation of the brain. Participants will undergo two brain scanning sessions, one before the first intervention and one immediately after the last Swedish massage or light touch therapy. The scans will last approximately 45 minutes. During the brain scanning sessions, information on heart rate, blood pressure, temperature and breathing will also be collected.
Sponsor: University of Utah
You may qualify if…
- ✓ Male or female
- ✓ aged ≥ 18 and \< 65 years old
- ✓ Medically stable
- ✓ Psychiatrically healthy as demonstrated by a structured clinical interview that elicits no previous or current Axis I psychopathology
- ✓ Ability to lie prone or supine for one hour at a time, given the nature of the massage intervention
- ✓ Subjects must have a permanent domicile
- ✓ Subjects must be able to comply with the research protocol
- ✓ Able to provide informed consent and willing to sign an approved consent form that conforms to federal and institutional guidelines.
You may not qualify if…
- ✕ Current (within 3 months of screening visit) nicotine use, illicit drug use, or long-term medication use that, in the opinion of the investigator, could alter the results of the study
- ✕ Pregnancy (per participant report, pregnancy testing not done for study)
- ✕ Usually is asleep during the daytime (ie due to Working third-shift), or any other behaviors that routinely disrupt normal diurnal (daily) rhythms
- ✕ Current (past month) rigorous dieting (defined as \<1200 calories per day for ≥2 consecutive days)
- ✕ In the month before screening visit, excessive regular use of alcohol, as defined by either of the following, twice a month or more often: (a drink is one 5 ounce glass of wine or equivalent) a. ingestion of 5 drinks or more in a 2 hour period b. ingestion of 7 drinks or more in a 24 hour period
- ✕ At screening visit, CURRENTLY using any of the following interventions because of psychological distress (for example, for treatment of anxiety and/or other psychiatric condition). (These types of treatments are also prohibited during the study period.) a. participating in psychotherapy b. participating in CAM (complementary and alternative medical interventions) c. taking medication(s) (for example anxiolytics, antidepressants, and other psychotropic medications)
- ✕ Participant meets criteria for current suicidal or homicidal ideation
- ✕ Subjects who have massages on a regular basis. Regular massage usage will be defined as receiving on average 4 or more massages/year for the last 5 years
Where it's recruiting
Salt Lake City
Source: ClinicalTrials.gov · NCT07190326 · last updated 2026-08-27