Early Double Sequential Defibrillation in Out of Hospital Cardiac Arrest
Eligible age
18+ yrs
Accepts
All genders
Locations
0 states
Healthy volunteers
No
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About this study
Some of the patients affected by Out-of-hospital cardiac arrest (OHCA) with ventricular fibrillation (VF)/ventricular tachycardia (VT) do not respond to initial defibrillation. The survival decreases with number of defibrillations required to terminate VF/VT. In 2022, one prospective cluster randomized trial showed increased survival among (OHCA) patients in refractory VF using Double Sequential Defibrillation (DSD). If DSD can increase survival among all patients in VF that dont respond to one defibrillation, i.e. before it has become refractory is not known. The aim of this trial is to assess survival with a double defibrillation strategy initiated as soon as possible among patients with Out of Hospital Cardiac Arrest with initial shockable rhythm and at least one failed standard defibrillation, compared with continued resuscitation using standard defibrillation.
Sponsor: Gabriel Riva
You may qualify if…
- ✓ OHCA patients with VT/VF at first rhythm analysis and at least one defibrillation performed in standard (A-L) position
You may not qualify if…
- ✕ Age \< 18 years
- ✕ Obvious pregnancy
- ✕ Known preexisting Do Not Attempt Resuscitation order
Source: ClinicalTrials.gov · NCT07174986 · last updated 2026-02-17