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RecruitingType 2 DiabetesAging

IH, Brain Health, and T2D

Eligible age

60–85 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

The purpose of this study is to use a randomized, placebo-controlled study design to rigorously examine the therapeutic potential of intermittent hypoxia (IH) for improving cerebrovascular health in older adults with and without type 2 diabetes mellitus (T2DM).

Sponsor: Darren P Casey

You may qualify if…

  • Willing and able to provide written, signed informed consent after the nature of the study has been explained, and prior to any research-related procedures.
  • Age is \> or = 60 and \< or = 85 years of age
  • Documented Type 2 diabetes
  • Scoring 26 or higher on the MoCA test
  • Willing and able to provide written, signed informed consent after the nature of the study has been explained, and prior to any research-related procedures.
  • Age is \> or = 60 and \< or = 85 years of age
  • Scoring 26 or higher on the MoCA test

You may not qualify if…

  • diagnosis of type 2 diabetes \< 1 year prior to enrollment
  • HbA1c \<6.5% or \>10.0%
  • body mass index \> 40 kg/m 2
  • incident cardiovascular events in the last year (heart attack, stroke)
  • symptomatic coronary artery disease and/or heart failure
  • uncontrolled hypertension
  • obstructive sleep apnea
  • pulmonary disease

Where it's recruiting

Iowa

Iowa City

Source: ClinicalTrials.gov · NCT07173543 · last updated 2026-03-13

IH, Brain Health, and T2D · TrialPath