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RecruitingRetinal DiseaseHealthyGlaucoma

Data Gathering for A10900

Eligible age

22+ yrs

Accepts

All genders

Locations

4 states

Healthy volunteers

Yes

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About this study

The objective of this study is to gather Optical Coherence Tomography (OCT) data on normal and diseased eyes

Sponsor: Optos, PLC

You may qualify if…

  • 1. Participants 22 years of age or older on the date of informed consent
  • 2. Participants able to understand the written informed consent and willing to participate as evidenced by signing the informed consent
  • 3. BCVA 20/40 or better in the study eye
  • 4. History of Visual field defects within the previous year from the study visit or measured the day of the study visit consistent with glaucomatous optic nerve damage with at least one of the following two findings:
  • 1. On pattern deviation (PD), there exists a cluster of 3 or more points in an expected location of the visual field depressed below the 5% level, at least 1 of which is depressed below the 1% level;
  • 2. Glaucoma hemi-field test "outside normal limits."
  • 5. Glaucomatous optic nerve damage as evidenced by any of the following optic disc or retinal nerve fiber layer structural abnormalities:
  • 1. Diffuse thinning, focal narrowing, or notching of the neuroretinal rim, especially at the inferior or superior poles with or without disc hemorrhage;

You may not qualify if…

  • 1. Participants unable to tolerate ophthalmic imaging
  • 2. Participants not able to obtain acceptable OCT images due to ocular media opacity or other reasons
  • 3. Participant has a condition or is in a situation which the investigator feels may put the participant at significant risk, may confound the study results, or may interfere significantly with the participant's participation in the study
  • 4. Presence of glaucoma or any ocular pathology other than a retinal pathology in the study eye as determined by self-report and/or investigator assessment at the study visit;
  • 1. Participants unable to tolerate ophthalmic imaging
  • 2. Participants not able to obtain acceptable OCT images due to ocular media opacity or other reasons
  • 3. Participant has a condition or is in a situation which the investigator feels may put the participant at significant risk, may confound the study results, or may interfere significantly with the participant's participation in the study
  • 4. No reliable visual field test result within the previous year from the study visit, defined as fixation losses \> 33% or false positives \> 33%, or false negatives \> 33% in the study eye

Where it's recruiting

California

Anaheim

Connecticut

West Hartford

Massachusetts

Wellesley Hills

Tennessee

Germantown

Source: ClinicalTrials.gov · NCT07149740 · last updated 2026-02-13