RecruitingCervical Mucus
Insights in Endocervical Mucus Secretion
Eligible age
21–40 yrs
Accepts
Women
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
Single arm interventional study looking at biological outcomes at 4 time points throughout the cycle before and after taking an oral gonadotropin-releasing hormone antagonist (gnRH). Samples of whole blood, endocervical mucus, endocervical biopsy, and vaginal swab will be collected.
Sponsor: Oregon Health and Science University
You may qualify if…
- ✓ Normal menstrual cycles of 25-35 days in length for at least the previous 3 cycles
- ✓ BMI \>18 and \<35
- ✓ Serum p4 \>= 3 ng/ml on single sample collected between days 18-25 of self-reported menstrual cycle
- ✓ Flexible schedule allowing blood draws on less than 48 hour notice
- ✓ In good general health
- ✓ Commit to using non-hormonal contraceptive methods without spermicide during study period except those prescribed in the experimental protocol
- ✓ No objections to taking study drugs
- ✓ No objections to refraining from intercourse the night before any sampling and willing to use condoms during vaginal intercourse
You may not qualify if…
- ✕ Oral contraceptive use or other hormone supplement within the preceding 2 months
- ✕ Current cervical infection
- ✕ Evidence of abnormal cervical cytology
- ✕ Use of any IUD for contraception
- ✕ Long-acting hormonal contraceptive use in the past 12 months (e.g., Depo-Provera)
- ✕ Contraindications to study drugs
- ✕ Current or past pregnancy within the previous 6 months or currently trying to conceive
- ✕ Desiring to conceive in the next 8 months
Where it's recruiting
Oregon
Portland
Source: ClinicalTrials.gov · NCT07111247 · last updated 2026-01-08