Strength Training Response of Muscle in GLP-1 Users
Eligible age
50+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
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About this study
GLP-1 medication is being prescribed for weight loss. However, GLP-1 medication may adversely affect muscle mass and muscle function. Moreover, any loss of muscle mass or muscle function with GLP-1 treatment may impair balance and increase fall risk. This is a particular concern among older adults already susceptible to the common muscle strength and muscle function loss with age, yet there is little evidence among this population. This study will address a gap in knowledge regarding the effects of GLP-1 treatment on muscle mass, muscle function, and balance/fall risk among adults age 50 and older.
Sponsor: Virginia Polytechnic Institute and State University
You may qualify if…
- ✓ Age, 50y+
- ✓ Be taking GLP-1 medicine (Weygovy or Zepbound) for 1 month or less
- ✓ Weight \<300 lb
- ✓ Pass a health and exercise readiness screening
You may not qualify if…
- ✕ Age \<50
- ✕ Weight \>300 lb
- ✕ Osteoporosis
- ✕ Active metabolic, neoplastic, or cardiovascular disease
- ✕ Unable or unwilling to provide consent
Where it's recruiting
Blacksburg
Source: ClinicalTrials.gov · NCT07104539 · last updated 2026-01-21