RecruitingObstructive Sleep Apnea (OSA)
Assessment of Circuit Rebreathing During CPAP Therapy
Eligible age
21–70 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
The goal of this research is to better understand how different CPAP mask designs affect airflow and rebreathing of exhaled carbon dioxide (CO₂) during sleep in individuals with obstructive sleep apnea (OSA).
Sponsor: Brigham and Women's Hospital
You may qualify if…
- ✓ Moderate to severe OSA (AHI\>20)
- ✓ Self-reported CPAP users or have previously used CPAP
- ✓ Self-reported holding pressure of maximum 13 cmH2O (if known)
- ✓ Age: 21-70
- ✓ BMI: 18-40 kg/m2
You may not qualify if…
- ✕ Self-reported severe mouth-breathing
- ✕ Requirement for nocturnal supplemental oxygen or other ventilatory support
- ✕ Severe cardiovascular or pulmonary disease
- ✕ Any unstable or acute medical condition
- ✕ Any additional sleep disorder, including insomnia, except for OSA.
Where it's recruiting
Massachusetts
Boston
Source: ClinicalTrials.gov · NCT07062770 · last updated 2025-07-14