RecruitingSCI - Spinal Cord Injury

Gut-Brain Neural Coupling in Spinal Cord Injury

Eligible age

18–70 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

See if you qualify for this study

Answer a few quick questions about your location and health. Takes about a minute.

The purpose of this research is to determine the effects of food on brain and stomach activity in persons with and without spinal cord injury (SCI).

Sponsor: University of Miami

✓ Adults, 18 to 70 years of age.
✓ Sex, male or female.
✓ Weight-stable (±3 kg) for the preceding 3 months (self-report).
✓ Physically inactive adults not meeting weekly activity guidelines (\<150 min/week) for the preceding 3 months (self-report).
✓ Fluent in written and spoken English.
✓ At least 12 months post-SCI, denoting chronic injury
✓ Complete American Spinal Injury Association (ASIA) Impairment Scale (AIS A) or motor-incomplete (AIS B) tetraplegia (SCI at or above C8 lesion)
✓ Able to self-feed (self-report)

✕ Do not meet the inclusion criteria.
✕ Current/regular smoker (defined by Center for Disease Control (CDC)/ National Institute of Health (NIH) as an adult who has smoked 100 cigarettes in his or her lifetime and who currently smokes either every day or every other day) (self-report).
✕ Currently dieting and/or trying to gain or lose weight.
✕ Vagus or recurrent laryngeal nerve injury (self-report).
✕ Uncontrolled thyroid disease, such that they are not on thyroid medication (e.g., levothyroxine) to treat the condition (self-report)
✕ Diabetes (type 1 or type 2) and/or currently taking anti-diabetic or glucagon-like peptide-1 (GLP-1)/dual agonist medications (self-report).
✕ Gastrointestinal disease (self-report), such as inflammatory bowel disease (e.g. Crohn's disease, ulcerative colitis), celiac disease, irritable bowel syndrome, gastroesophageal reflux disease, peptic ulcer disease, chronic pancreatitis, liver cirrhosis, and any condition requiring gastrointestinal surgery (e.g., bowel resection, colostomy, or ileostomy).
✕ Swallowing disorder (self-report).

Miami

Source: ClinicalTrials.gov · NCT07052344 · last updated 2026-07-17