Biannual Review of Exhaled Air and Trends in Health Evaluation in COPD
Eligible age
40+ yrs
Accepts
All genders
Locations
0 states
Healthy volunteers
No
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About this study
This study aims to evaluate how airway inflammation, lung function, and symptoms change over time in people with chronic obstructive pulmonary disease (COPD). Airway inflammation will be assessed using a simple breath test (FeNO) and a small blood sample to measure eosinophils, a type of white blood cell. Participants will be followed for one year, with three study visits (at the start, 6 months, and 12 months). The goal is to understand how these markers evolve and whether they differ between people who experience a worsening of symptoms (called exacerbations) and those who remain stable. All tests except for a small extra blood draw are part of routine COPD care. Participation does not affect standard treatment.
Sponsor: Universitair Ziekenhuis Brussel
You may qualify if…
- ✓ Adults aged ≥ 40 years
- ✓ Diagnosed with COPD according to GOLD criteria
- ✓ Attending routine follow-up visits every 6 months
- ✓ Ability to provide informed consent
You may not qualify if…
- ✕ Recent respiratory tract infection or exacerbation (either moderate or se-vere) (\<4 weeks before inclusion)
- ✕ Dominant asthmatic phenotype (ACO with asthma predominance)
- ✕ Severe comorbidities interfering with participation or follow-up
Source: ClinicalTrials.gov · NCT07045948 · last updated 2025-09-11