Virtual Reality Treatment for Adults With Chronic Back Pain (VRNT)
Eligible age
18–85 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
Participants with chronic back pain will complete an online Qualtrics eligibility survey. After signing a consent form, eligible participants enter a two-week baseline period ("Baseline Period"), during which they complete two assessments of the Primary and Secondary Outcome Measures and Potential Mediators. After the baseline period, participants are randomized into a Virtual Reality group: VR Distraction-based Therapy or VR Skills-based Therapy, with a 1:1 allocation ratio of participants to each treatment. Both groups receive education on pain neuroscience and complete training on the use of the VR hardware and software. Next, both groups complete an intervention for 8 weeks ("Treatment Period"), after which they return the VR equipment. Several surveys are administered online during the Treatment Period. After the Treatment Period, both groups complete three post-treatment surveys at weeks 8, 20, and 32.
Sponsor: CognifiSense Inc.
You may qualify if…
- ✓ Men and women aged 18 to 85.
- ✓ Self-reported diagnosis of chronic low back pain without radicular symptoms.
- ✓ Chronic low back pain duration of 6 months or more, and pain at least half the days in the last 6 months.
- ✓ Lower back pain as primary chronic pain complaint (greater than pain in other bodily regions).
- ✓ Average pain intensity of 4 or more out of 10 for the past week (from BPI-SF).
- ✓ English fluency (8th grade level).
- ✓ Willing to comply with study procedures/restrictions.
- ✓ Access to Wi-Fi.
You may not qualify if…
- ✕ Applicants, who are pregnant, planning pregnancy, or breastfeeding
- ✕ Back pain associated with compensation / litigation within 1 year.
- ✕ Leg pain greater than back pain (suggests neuropathic pain; may be less responsive to psychological therapy).
- ✕ Chronic pain other than chronic back pain.
- ✕ Diagnoses of schizophrenia, multiple personality dissociative identity disorder.
- ✕ History of major depressive disorder not controlled with medication or other conditions that produce significant cognitive or emotional disability.
- ✕ History of substance abuse.
- ✕ Inability to undergo MRI (determined at screening; see XVI: Risks to Participants).
Where it's recruiting
Boulder
Source: ClinicalTrials.gov · NCT07033195 · last updated 2026-04-02