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RecruitingObesity

Upper Body Subcutaneous Exosome Release in Response to a Meal in Obesity

Eligible age

18–55 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

Yes

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About this study

The purpose of this study is to understand the specific outflow and difference between normal weight and volunteers with obesity of upper body subcutaneous adipose tissue in response to a mixed meal challenge by site specific cannulation of the superior epigastric vein. We will characterize the exosome signatures in response to a meal and compare to the exosome signature of arterialized venous plasma samples.

Sponsor: Mayo Clinic

You may qualify if…

  • All women must be premenopausal

You may not qualify if…

  • Participants taking medications know to affect blood flow (statins, β-blockers) or fatty acid or adipose tissue metabolism (TZDs, high dose fish oil supplements)
  • Diabetes, history of cardiovascular disease
  • Allergy to lidocaine
  • Post-menopausal women
  • Pregnant

Where it's recruiting

Minnesota

Rochester

Source: ClinicalTrials.gov · NCT07031297 · last updated 2026-08-05

Upper Body Subcutaneous Exosome Release in Response to a Meal in Obesi · TrialPath