REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults
Eligible age
18+ yrs
Accepts
All genders
Locations
11 states
Healthy volunteers
No
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About this study
This study is researching an experimental drug called REGN7508 (called "study drug"). The study is focused on adults undergoing elective, unilateral (one side) total knee replacement surgery. The aim of the study is to see how effective the study drug is at preventing Venous Thromboembolism (VTE) and other related diseases after total knee replacement surgery. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug * How much study drug is in the blood at different times * Whether the body makes antibodies against the study drug (which could make the study drug less effective or could lead to side effects)
Sponsor: Regeneron Pharmaceuticals
Where it's recruiting
Sheffield
Riverside
Englewood
Delray Beach · Miami · Pensacola · Sarasota …
Baltimore
Boston
Westwood
Durham
Plymouth Meeting
Bellaire · Dallas · Houston · McAllen …
St. George
Source: ClinicalTrials.gov · NCT07015905 · last updated 2026-07-13