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RecruitingReducing Pain With Nexplanon Implant Insertion

Vapocoolant Spray to Reduce Pain With Nexplanon Insertion

Eligible age

14+ yrs

Accepts

Women

Locations

1 state

Healthy volunteers

Yes

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About this study

The purpose of this study is to assess if Pain Ease vapocoolant spray decreases pain associated with lidocaine injection during Nexplanon insertion procedures.

Sponsor: Queen's Medical Center

You may qualify if…

  • At least 14 years or older
  • Undergoing an etonogestrel implant insertion in the arm in POB1 Suite 1004 or POB2 Suite 402
  • English speaking
  • Able and willing to sign the informed consent form and agree to terms of the study

You may not qualify if…

  • Required or requested narcotics, anxiolytics, IV sedation, or general anesthesia for the procedure
  • Known previous exposure to vapocoolant spray
  • Nexplanon removal and reinsertion same day during visit in the same arm
  • Contraindications to vapocoolant spray components (ethyl chloride and 1,1,1,3,3-pentafluoropropane/1,1,1,2-tetrafluroethane)
  • Unable to provide written, informed consent in English

Where it's recruiting

Hawaii

Honolulu · Waimea

Source: ClinicalTrials.gov · NCT06933381 · last updated 2026-01-09

Vapocoolant Spray to Reduce Pain With Nexplanon Insertion · TrialPath