RecruitingMajor Depressive DisorderBipolar DisorderMild Cognitive Impairment
Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
The purpose of this research is to measure brain activity in individuals with mood disorders and memory problems using a simple, safe, and noninvasive method called functional near-infrared spectroscopy (fNIRS). By comparing brain activity across different groups and relating it to symptom severity, this study aims to improve our understanding of how these conditions affect the brain.
Sponsor: Mayo Clinic
You may qualify if…
- ✓ General Inclusion Criteria (across all diagnostic groups):
- ✓ 18 years and older
- ✓ Ability to provide written informed consent
- ✓ Adequate cognitive and language abilities to understand and complete study tasks, including clinical assessments and fNIRS procedures
- ✓ Confirmed clinical diagnosis of major depressive disorder, bipolar disorder, or mild cognitive impairment (MCI)
- ✓ Stable psychiatric or cognitive condition, without acute episodes requiring immediate intervention
- ✓ Specific Inclusion Criteria (for diagnostic groups):
- ✓ Healthy control
You may not qualify if…
- ✕ General Exclusion Criteria (across all diagnostic groups):
- ✕ Active primary psychotic or substance use disorders (except nicotine dependence) within the past year
- ✕ Any severe or unstable medical condition that could interfere with participation or data collection
- ✕ Any active neurological condition (including seizure disorder, traumatic brain injury, stroke) that could affect cognitive functioning or brain imaging results
- ✕ Inability to comply with study procedures, including cognitive testing, fNIRS assessment, or other assessments required by the protocol
- ✕ Pregnant women will be excluded due to potential physiological changes that could affect study outcomes
- ✕ Specific Exclusion Criteria (for diagnostic groups):
- ✕ Healthy control
Where it's recruiting
Minnesota
Rochester
Source: ClinicalTrials.gov · NCT06897670 · last updated 2026-04-29