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RecruitingPerinatal Spinal Cord Injury

Understanding Perinatal Spinal Cord Injury

Eligible age

3–8 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The purpose of this study is to deepen our understanding of children who have a cervical spinal cord injury obtained in utero or at birth and examine the effects of tailored activity-based recovery training (ABRT) in combination with transcutaneous spinal cord stimulation (scTS). This is a within subjects, pre-post design study. Neurophysiological, sensorimotor, and autonomic assessments will occur pre, interim, and post 40 sessions of ABRT in conjunction with scTs.

Sponsor: University of Louisville

You may qualify if…

  • ✓ diagnosed with a perinatal (injured in utero or at birth), upper motor neuron spinal cord injury involving cervical spinal levels
  • ✓ discharged from inpatient hospitalization/inpatient rehabilitation

You may not qualify if…

  • ✕ Botox use within the past 3 months
  • ✕ Current oral baclofen or baclofen pump use
  • ✕ Musculoskeletal impairment limiting range of motion (e.g. severe scoliosis), unhealed fracture, or other medical impairment limiting study participation
  • ✕ History of allodynia (heightened skin sensitivity typically at the level of the lesion site)
  • ✕ History of scoliosis surgery
  • ✕ Ventilator-dependence
  • ✕ Unwillingness to wean from daytime use of thoroco/lumbosacral orthosis and ankle/foot orthosis during the intervention period

Where it's recruiting

Kentucky

Louisville

Source: ClinicalTrials.gov · NCT06808035 · last updated 2026-09-11

Understanding Perinatal Spinal Cord Injury · TrialPath