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RecruitingPrimary Photoreceptor DiseaseRetinitis Pigmentosa (RP)Usher Syndrome

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

Eligible age

18+ yrs

Accepts

All genders

Locations

4 states

Healthy volunteers

No

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About this study

Study OpCT-001-101 is a Phase 1/2a first-in-human, multisite, 2-part interventional study to evaluate the safety, tolerability, and the effect on clinical outcomes of OpCT-001 in approximately 54 adults with primary photoreceptor (PR) disease. Phase 1 focuses on safety and features a dose-escalation design. Phase 2 is designed to gather additional safety data and assess the effect of OpCT-001 on measures of visual function, functional vision, and anatomic measures of engraftment in different clinical subgroups.

Sponsor: BlueRock Therapeutics

Where it's recruiting

Florida

Miami

Pennsylvania

Philadelphia

Texas

Dallas

Wisconsin

Madison

Source: ClinicalTrials.gov · NCT06789445 · last updated 2026-04-13