RecruitingChronic Pelvic Pain Syndrome (CPPS)Chronic Pelvic Pain SyndromeChronic Pelvic Pain
National Program to Overcome Pelvic Pain studY (POPPY)
Eligible age
18+ yrs
Accepts
Women
Locations
1 state
Healthy volunteers
No
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About this study
A randomized, parallel-group, investigator-blinded, comparative effectiveness trial of a fully remote, videoconference-based pelvic floor yoga program versus a physical conditioning program for women with chronic pelvic pain syndrome.
Sponsor: University of California, San Francisco
You may qualify if…
- ✓ Women (individuals reporting female sex assigned at birth who self-identify as women or non-binary) aged 18 years or older
- ✓ Report chronic or recurrent pain in the pelvis (between or below the anterior iliac crests) for at least 6 months
- ✓ Report at least moderate pain intensity based on a screening pain log
- ✓ Report prior clinical evaluation of their pelvic pain by a healthcare professional including at least a superficial pelvic exam
- ✓ Willing to refrain from initiating new clinical treatments that may affect their pain during the study period
You may not qualify if…
- ✕ Report pelvic pain occurring exclusively with menses or exclusively during sexual intercourse (although candidates with at least some pain between menses or intercourse are still eligible)
- ✕ Participation in organized yoga classes or muscle strengthening programs (e.g., Pilates) in the past 4 weeks, or any prior yoga therapy specifically directed at pelvic pain
- ✕ Lacking technical requirements to complete intervention classes by video, including no access to broadband internet or a Zoom-compatible device larger than a smartphone \[display screen at least 7 inches in diagonal\] (although the study team may loan devices to participants from underrepresented backgrounds)
- ✕ Currently pregnant (by self-report or screening test), pregnant within the past 12 weeks, or planning pregnancy during the study period
- ✕ Diagnosed with an alternate, reversible cause of pelvic pain that is unlikely to respond to yoga and requires another treatment modality (e.g., current pelvic infection or a gynecologic dermatosis)
- ✕ Surgery or irradiation to the genital or pelvic structures within the past 12 weeks, or anticipating upcoming surgery or irradiation to these structures during the study period
- ✕ Initiation, dose escalation, or weaning of pharmacologic agents that may affect pelvic pain severity in the past 4 weeks, such as analgesics, antidepressants, or anticonvulsants-(however, women on stable doses of these medications for at least 4 weeks will still be eligible)
- ✕ Use of formal psychological therapies specifically for pelvic pain (e.g., systematic desensitization, cognitive therapy, relaxation therapy) within 4 weeks of screening, or plans to engage in these therapies during the study period
Where it's recruiting
California
San Francisco
Source: ClinicalTrials.gov · NCT06778070 · last updated 2026-03-06