RecruitingEndometrioma
Endometrioma Sclerotherapy and Ovarian Preservation
Eligible age
18–45 yrs
Accepts
Women
Locations
0 states
Healthy volunteers
No
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About this study
A randomised controlled trial assessing ovarian reserve after laparoscopic ethanol sclerotherapy of ovarian endometrioma compared to standard treatment of surgical excision of endometrioma. Secondary outcomes will include endometrioma recurrence, symptomatology and inflammatory environment.
Sponsor: Chelsea and Westminster NHS Foundation Trust
You may qualify if…
- ✓ Female (XX genotype, assigned female at birth)
- ✓ Age 18-40
- ✓ Finding of suspected uni- or bi-lateral ovarian endometrioma(ta) of ≥ 2cm on TVUSS and/or pelvic MRI scan (TVUSS, a uni- or multi-locular ovarian cystic lesion with low level echoes and diffuse homogeneous ground glass appearance; MRI any of, ovarian lesion hyperintense T1 without loss of signal on T1 fat-suppressed images, hypointense T2 exhibiting shading sign and/or T2 dark spot sign, variable restricted diffusion on DWI)
- ✓ Appropriate to be listed for laparoscopic excision of endometrioma (Endometrioma ≥2cm, pain symptoms attributable to endometriosis where medical management is unsuccessful or unacceptable to the patient, to facilitate ART)
You may not qualify if…
- ✕ Postmenopausal status
- ✕ Suspicion of malignancy
- ✕ Unable to undergo TVUSS
- ✕ Declines to take part in the study
- ✕ Unable to understand verbal or written information in English
- ✕ Lack of capacity to consent at the point of recruitment
- ✕ Known safeguarding issues
Source: ClinicalTrials.gov · NCT06775769 · last updated 2025-11-25