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RecruitingNon-small Cell Lung Cancer

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

Eligible age

18+ yrs

Accepts

All genders

Locations

18 states

Healthy volunteers

No

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About this study

This is a Phase 2/3, multisite, randomized, open-label study in participants with first-line non-small cell lung cancer (NSCLC). This study includes two substudies (substudy A and substudy B) that will recruit participants according to histological subtypes due to differences in chemotherapy choice for standard-of-care and type of NSCLC.

Sponsor: BioNTech SE

Where it's recruiting

Alabama

Birmingham

Alaska

Anchorage

California

Concord · La Jolla

Florida

Clermont · Orange City · Stuart · Tampa

Indiana

Fort Wayne

Iowa

Cedar Rapids · Iowa City

Kentucky

Elizabethtown

Maryland

Frederick

Missouri

Columbia · Fenton

Nebraska

Hastings

New Jersey

East Brunswick · Florham Park · Paramus

New York

Stony Brook · White Plains

Source: ClinicalTrials.gov · NCT06712316 · last updated 2026-07-01

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With C · TrialPath