Tissue Repair Gel in Venous Leg Ulcers (US)
Eligible age
18+ yrs
Accepts
All genders
Locations
13 states
Healthy volunteers
No
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About this study
The goal of this clinical trial is to learn if TR987 0.1% gel + Standard of Care works better than Standard of Care alone to treat Venous Leg Ulcers (VLUs). It will also provide additional information about the safety of drug TR987 0.1% gel.
Sponsor: TR Therapeutics
You may qualify if…
- ✓ Adults 18 years and older
- ✓ Venous insufficiency has been clinically diagnosed clinically and medically confirmed.
- ✓ Females who are neither pregnant nor breastfeeding and if of child-bearing potential are on an acceptable method of birth control.
- ✓ The Venous Ulcer should be between 2 cm2 and 12 cm2 at randomization.
- ✓ Target ulcer age must be ≥ 4 weeks at Screening.
- ✓ Participants must have adequate arterial flow as confirmed by ABI/TBI, TB, SPP, TCPo2, or Duplex Doppler.
- ✓ Body mass index (BMI) ≤ 50 kg/m2.
- ✓ HbA1C ≤12%.
You may not qualify if…
- ✕ Target ulcer has been treated with prohibited medications or therapies.
- ✕ History of radiation at the target ulcer site.
- ✕ Target ulcer decreases in area by 30% or more during screening period.
- ✕ History of osteomyelitis at the target ulcer within 6 months of screening.
- ✕ Participants considered nutritionally deficient.
Where it's recruiting
Tucson
Castro Valley · Fresno · Los Angeles · San Francisco …
Deerfield Beach · Hollywood · Jacksonville · Miami …
Chicago · O'Fallon · Springfield
Bossier City · Lafayette
D'Iberville · McComb
New York · Syosset
Winston-Salem
Grove City · Mentor
Tulsa
Philadelphia
Fort Worth · Houston · San Antonio
Source: ClinicalTrials.gov · NCT06707090 · last updated 2026-02-12