RecruitingPulmonary Embolism
A Study of Mobility Outcomes in Post-Pulmonary Embolic Disease
Eligible age
18–80 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The purpose of this study is to develop a unique structure and delivery of home-based exercise through multidisciplinary expertise of cardiovascular medicine specialists and cardiac physiologists using an Interactive Care Plan.
Sponsor: Mayo Clinic
You may qualify if…
- ✓ Acute intermediate-risk PE, defined as:
- ✓ Intraluminal filling defect in segmental or larger vessels on computed tomography pulmonary angiography or high-probability ventilation/perfusion scan AND
- ✓ Evidence of right ventricular enlargement by computed tomography (RV to LV ratio \>1) or echocardiography; and/or right ventricular dysfunction by transthoracic echocardiography. These imaging characteristics must be in the setting of acute PE rather than explained by a prior chronic condition.
- ✓ Acute high-risk PE, defined as:
- ✓ Intraluminal filling defect in segmental or larger vessels on computed tomography pulmonary angiography or high-probability ventilation/perfusion scan AND
- ✓ Evidence of right ventricular enlargement by computed tomography (RV to LV ratio \>1) or echocardiography; and/or right ventricular dysfunction by transthoracic echocardiography. These imaging characteristics must be in the setting of acute PE rather than explained by a prior chronic condition; AND
- ✓ Hypotension (systolic blood pressure \< 90 mm Hg sustained for more than 15 minutes; or requiring vasopressors) or cardiogenic shock due to acute pulmonary embolism.
You may not qualify if…
- ✕ Inability to ambulate independently, which is necessary to perform 6MWD (may be self-reported or as deemed by physical therapy during inpatient evaluation).
- ✕ If patient requires supplemental oxygen during ambulation, this does not exclude patient from participation and will be noted during eCRF.
- ✕ Prior history of pulmonary embolism
- ✕ History of CTEPH or pulmonary arterial hypertension
- ✕ Unable to read a questionnaire in English
- ✕ Unable to return for baseline, 3- or 6-month follow-up visit
- ✕ Pregnancy-associated pulmonary embolism
- ✕ Life expectancy \<1 year based on comorbidities
Where it's recruiting
Minnesota
Rochester
Source: ClinicalTrials.gov · NCT06695247 · last updated 2026-08-10