Efficacy of Nerve Block Versus Botox in Chronic Migraine Management
Eligible age
18–65 yrs
Accepts
All genders
Locations
0 states
Healthy volunteers
No
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About this study
The goal of this clinical trial is to determine whether nerve block injections (specifically, supratrochlear and greater occipital nerve injections) are as effective as Botulinum toxin A (Botox) injections in treating chronic migraine in adults. The main questions it aims to answer are: * Do nerve block injections reduce the number of monthly migraine days compared to baseline? * Are there any differences in the frequency of migraine-related symptoms between the nerve block and Botox treatment groups? * Which treatment leads to higher patient satisfaction and improved quality of life? Participants in this study will: * Receive either nerve block injections or Botox injections every 12 weeks. * Visit the clinic once every month for follow-ups and assessments. * Maintain a headache diary to record the frequency and severity of their migraines and any adverse effects experienced. * Researchers will compare the outcomes of the two groups to determine if one treatment is superior in terms of efficacy and patient satisfaction.
Sponsor: Zagazig University
You may qualify if…
- ✓ Adults aged 18 to 65 years.
- ✓ Diagnosis of chronic migraine, defined as having headaches on 15 or more days per month for more than three months, with at least 8 of those days meeting criteria for migraine.
- ✓ Ability to provide informed consent and comply with study requirements.
- ✓ No changes in prophylactic migraine medications in the last 3 months.
You may not qualify if…
- ✕ History of allergy or hypersensitivity to local anesthetics or Botulinum toxin.
- ✕ Previous nerve block or Botox treatment within the last 6 months.
- ✕ Significant comorbid psychiatric or neurological disorders that could interfere with study participation or evaluation.
- ✕ Pregnancy or breastfeeding.
- ✕ Contraindications to either treatment as per product labels.
Source: ClinicalTrials.gov · NCT06684249 · last updated 2024-11-12